Aqueous solutions of pyrimidine nucleic acid bases . Solute – solvent interactions
نویسنده
چکیده
The data previously reported on the enthalpy of hydration, partial molar volumes and heat capacities of alkylated pyrimidine nucleic acid bases, e.g. uracil, thymine and cytosine, were correlated with the following structural parameters: molecular volume, volume of solvation shell, accessible molecular surface area and its atomic partition as well as and electrostatic potential charge. The simple additivity scheme of group contributions was also taken into consideration. The correlations obtained are presented and discussed. The results of the investigations clearly show that polar interactions are decisive in structuring the water around the solute molecules.
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